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DIAsource Immunoassays Research Activities

DIAsource Immunoassays main research activities are centered on investigating various forms of Vitamin D and developing appropriate technologies for measuring these forms in body fluids using new separation techniques and advanced antibody enhancement methods and immune-chemistry technologies.

Although many companies have recently developed assays for measurement of 25 OH Vitamin D status, there remains a lot of confusion about the quality of these assays and particularly about the pre-treatment efficiency (displacement of the vitamin D molecule from DBP) and the calibration. DIAsource Immunoassays is involved in research to understand better the pretreatment process and developing new more efficient methods for pretreatment of patient samples. We further are specifically involved in understanding the role of the most important fractions of 25OH Vitamin D in blood: Total, Free and Bioavailable fractions.

It is our aim to bring to market new assays that measure these different fractions in serum by using immunochemistry techniques based on our patented 25OH Vitamin D monoclonal antibodies.

Some of these assays are brought to market in a RUO format first and will further be refined together with University and Clinical institutes to make them a validated diagnostic tool for IVD use.

DIAsource Immunoassays R&D team has recently developed a prototype of Lateral Flow ImmunoAssay (LFIA) for the rapid assessment of the Vitamin D status in a patient sample. This Point Of Care Test (POCT) allows for the quantitative measurement of 25OH Vitamin D in serum using a fluorescence reader. Further development should reduces the assay time and permits the use of whole blood.

Understanding the clinical importance of the different fractions of 25OH Vitamin D is an essential step for the determination of normal values and recommendations for dietary Vitamin D supplementation.


DIAsource ImmunoAssays SA
BE 0457.934.723
Rue du Bosquet, 2 | 1348 Louvain-la-Neuve - Belgium
Tel +32 10 84 99 11 | Fax +32 10 84 99 90

CLOSING DAYS 2019 : 1/01-22/04-01&30/05-10/06-21/07-15/08-01&11/11-25/12

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DIAsource ImmunoAssays (formerly BioSource), experienced diagnostic manufacturer of RIA-ELISA-LIA immunoassays, validation on automates, large scale production of Antibodies-Point of Care Tests.

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